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Therapy Name | HMPL-306 |
Synonyms | |
Therapy Description |
HMPL-306 specifically inhibits mutant IDH1/2, resulting in decreased conversion of alpha-ketoglutarate into 2-hydroxyglutarate, and potentially leading to inhibition of of IDH1/2 mutant tumor cell proliferation (NCI Drug Dictionary, J Clin Oncol 2025 43: 16_suppl, 2013). |