HMPL-306
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| Drug Name | HMPL-306 |
| Trade Name | |
| Synonyms | HMPL 306|HMPL306 |
| Drug Descriptions |
HMPL-306 specifically inhibits mutant IDH1/2, resulting in decreased conversion of alpha-ketoglutarate into 2-hydroxyglutarate, and potentially leading to inhibition of of IDH1/2 mutant tumor cell proliferation (NCI Drug Dictionary, J Clin Oncol 2025 43: 16_suppl, 2013). |
| DrugClasses | IDH Inhibitor (Pan) 3 |
| CAS Registry Number | NA |
| NCIT ID | C175602 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| HMPL-306 | HMPL-306 | 5 | 2 |
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