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Drug Name | MCY-M11 |
Trade Name | |
Synonyms | anti-mesothelin mRNA-transfected autologous PBMCs MCY-M11 |
Drug Descriptions |
MCY-M11 consists of autologous peripheral blood mononuclear cells modified to express an mRNA construct that encodes a mesothelin-targeting chimeric antigen receptor (CAR), which potentially induces phagocytosis and increases cytotoxicity against tumor cells expressing mesothelin (NCI Drug Dictionary; J Clin Oncol 2020 38:15_suppl, 3014). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C155775 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
MCY-M11 | MCY-M11 | 0 | 1 |