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Therapy Name | MCY-M11 |
Synonyms | |
Therapy Description |
MCY-M11 consists of autologous peripheral blood mononuclear cells modified to express an mRNA construct that encodes a mesothelin-targeting chimeric antigen receptor (CAR), which potentially induces phagocytosis and increases cytotoxicity against tumor cells expressing mesothelin (NCI Drug Dictionary; J Clin Oncol 2020 38:15_suppl, 3014). |