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Drug Name | TSA/TAA-specific TCR engineered T cells |
Trade Name | |
Synonyms | TCR-transduced T cells|TSA-reactive TCR-engineered T cells |
Drug Descriptions |
TSA/TAA-specific TCR engineered T cells consist of T-lymphocytes engineered to express a T-cell receptor (TCR) that targets tumor-specific antigens (TSA) or tumor-associated antigens (TAA), which potentially induces cytotoxic response against TSA or TAA-expressing tumor cells (PMID: 20454585). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
CDX-1140 + Pembrolizumab + TSA/TAA-specific TCR engineered T cells | CDX-1140 Pembrolizumab TSA/TAA-specific TCR engineered T cells | 0 | 2 |
TSA/TAA-specific TCR engineered T cells | TSA/TAA-specific TCR engineered T cells | 0 | 0 |