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Drug Name | Catumaxomab |
Trade Name | |
Synonyms | Removab |
Drug Descriptions |
Catumaxomab is a trifunctional bispecific antibody that binds to Epcam and Cd3, and will bind to accessory immune cells such as macrophages, dendritic cells and natural killer cells, which redirects cytotoxic T-lymphocytes against tumor cells expressing Epcam, potentially inducing lysis of Epcam-expressing tumor cells (PMID: 32438548, PMID: 21188120). |
DrugClasses | |
CAS Registry Number | 509077-98-9 |
NCIT ID | C62445 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Catumaxomab | Catumaxomab | 0 | 1 |