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Therapy Name | Catumaxomab |
Synonyms | |
Therapy Description |
Catumaxomab is a trifunctional bispecific antibody that binds to Epcam and Cd3, and will bind to accessory immune cells such as macrophages, dendritic cells and natural killer cells, which redirects cytotoxic T-lymphocytes against tumor cells expressing Epcam, potentially inducing lysis of Epcam-expressing tumor cells (PMID: 32438548, PMID: 21188120). |