NT219
Drug Detail
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| Drug Name | NT219 |
| Trade Name | |
| Synonyms | NT-219|NT 219 |
| Drug Descriptions |
NT219 is a small molecule that inhibits both Stat3 and Irs1/2, resulting in decreased Stat3 phosphorylation and increased degradation of Irs1/2, and potentially leading to tumor growth inhibition (Cancer Res 2020;80(16 Suppl):Abstract nr 5639). |
| DrugClasses | STAT3 Inhibitor 26 |
| CAS Registry Number | NA |
| NCIT ID | C178343 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Cetuximab + NT219 | Cetuximab NT219 | 0 | 2 |
| NT219 | NT219 | 0 | 1 |
| NT219 + Pembrolizumab | NT219 Pembrolizumab | 0 | 1 |
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