BNT111
Drug Detail
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| Drug Name | BNT111 |
| Trade Name | |
| Synonyms | BNT-111|BNT 111 |
| Drug Descriptions |
BNT111 is a liposomal RNA vaccine comprising mRNA transcripts that encode wild-type NY-ESO1, MAGE-A3, TYR (aa 1-477), and TPTE tumor specific antigens (TSAs), which is targeted to and expressed in dendritic cells, potentially inducing cytotoxic T-cell response against NY-ESO1, MAGE-A3, TYR, and TPTE expressing tumor cells (PMID: 32728218). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C122396 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| BNT111 | BNT111 | 0 | 1 |
| BNT111 + Cemiplimab | BNT111 Cemiplimab | 0 | 1 |
| BNT111 + Nivolumab | BNT111 Nivolumab | 0 | 0 |
| BNT111 + Pembrolizumab | BNT111 Pembrolizumab | 0 | 0 |
| BNT111 + unspecified PD-1 antibody | BNT111 unspecified PD-1 antibody | 0 | 0 |
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