MKC-3946
Drug Detail
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| Drug Name | MKC-3946 |
| Trade Name | |
| Synonyms | MKC 3946|MKC3946 |
| Drug Descriptions |
MKC-3946 is small molecule drug that targets the endoribonuclease domain of Ire1 alpha (ERN1) and inhibits XBP1 splicing, potentially resulting in increased apoptosis and decreased tumor growth (PMID: 22538852). |
| DrugClasses | |
| CAS Registry Number | 1093119-54-0 |
| NCIT ID | NA |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| BMI-135 + MKC-3946 | BMI-135 MKC-3946 | 0 | 0 |
| Bortezomib + MKC-3946 | Bortezomib MKC-3946 | 0 | 0 |
| MKC-3946 | MKC-3946 | 0 | 0 |
| MKC-3946 + Tanespimycin | MKC-3946 Tanespimycin | 0 | 0 |
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