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Drug Name Bortezomib
Trade Name Velcade
Synonyms
Drug Descriptions

Velcade (bortezomib) is a reversible proteasome inhibitor that inhibits survival of malignant cells and regulates bone remodeling (PMID: 26579531). Velcade (bortezomib) is FDA approved for the treatment of mantle cell lymphoma and multiple myeloma (FDA.gov).

DrugClasses
CAS Registry Number 179324-69-7
NCIT ID C1851

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Therapy Name Drugs Efficacy Evidence Clinical Trials
ABBV-621 + Bortezomib + Dexamethasone ABBV-621 Bortezomib Dexamethasone 0 1
Acalabrutinib + Bortezomib + Cyclophosphamide + Doxorubicin + Prednisone + Rituximab Acalabrutinib Bortezomib Cyclophosphamide Doxorubicin Prednisone Rituximab 0 1
Acalabrutinib + Bortezomib + Cyclophosphamide + Doxorubicin + Prednisone + Rituximab Hyaluronidase Acalabrutinib Bortezomib Cyclophosphamide Doxorubicin Prednisone Rituximab Hyaluronidase 0 1
Aldoxorubicin + Bendamustine + Bortezomib Aldoxorubicin Bendamustine Bortezomib 0 0
Alisertib + Bortezomib + Rituximab Alisertib Bortezomib Rituximab 0 1
AO-176 + Bortezomib + Dexamethasone AO-176 Bortezomib Dexamethasone 0 1
BC2059 + Bortezomib BC2059 Bortezomib 0 0
belantamab mafodotin-blmf + Bortezomib + Dexamethasone Bortezomib Dexamethasone belantamab mafodotin-blmf 0 2
belantamab mafodotin-blmf + Bortezomib + Dexamethasone + Lenalidomide Bortezomib Dexamethasone Lenalidomide belantamab mafodotin-blmf 0 2
Bendamustine + Bortezomib + Ofatumumab Bendamustine Bortezomib Ofatumumab 0 1
Bendamustine + Bortezomib + Pegylated liposomal doxorubicin Bendamustine Bortezomib Pegylated liposomal doxorubicin 0 1
Bendamustine + Bortezomib + Rituximab Bendamustine Bortezomib Rituximab 0 0
Bevacizumab + Bortezomib Bevacizumab Bortezomib 0 1
Bevacizumab + Bortezomib + Temozolomide Bevacizumab Bortezomib Temozolomide 0 1
Birabresib + Bortezomib Birabresib Bortezomib 0 0
Bortezomib Bortezomib 0 44
Bortezomib + BX-912 BX-912 Bortezomib 0 0
Bortezomib + Calaspargase pegol-mknl + Cyclophosphamide + Cytarabine + Daunorubicin + Dexamethasone + Hydrocortisone + Mercaptopurine + Methotrexate + Vincristine Sulfate Bortezomib Calaspargase pegol-mknl Cyclophosphamide Cytarabine Daunorubicin Dexamethasone Hydrocortisone Mercaptopurine Methotrexate Vincristine Sulfate 0 1
Bortezomib + Calaspargase pegol-mknl + Cytarabine + Daunorubicin + Dexamethasone + Hydrocortisone + Methotrexate + Vincristine Sulfate Bortezomib Calaspargase pegol-mknl Cytarabine Daunorubicin Dexamethasone Hydrocortisone Methotrexate Vincristine Sulfate 0 1
Bortezomib + Cannabidiol Bortezomib Cannabidiol 0 1
Bortezomib + Carfilzomib + Clarithromycin Bortezomib Carfilzomib Clarithromycin 0 1
Bortezomib + CC-92480 + Dexamethasone Bortezomib CC-92480 Dexamethasone 0 2
Bortezomib + Ciltacabtagene autoleucel + Cyclophosphamide + Dexamethasone + Fludarabine + Pomalidomide Bortezomib Ciltacabtagene autoleucel Cyclophosphamide Dexamethasone Fludarabine Pomalidomide 0 1
Bortezomib + Cisplatin + Pembrolizumab Bortezomib Cisplatin Pembrolizumab 0 1
Bortezomib + Cladribine + Rituximab Bortezomib Cladribine Rituximab 0 1
Bortezomib + Clofarabine Bortezomib Clofarabine 0 1
Bortezomib + Cyclophosphamide Bortezomib Cyclophosphamide 0 2
Bortezomib + Cyclophosphamide + Cytarabine + Dexamethasone + Mercaptopurine + Methotrexate + Pegaspargase + Vincristine Sulfate Bortezomib Cyclophosphamide Cytarabine Dexamethasone Mercaptopurine Methotrexate Pegaspargase Vincristine Sulfate 0 1
Bortezomib + Cyclophosphamide + Cytarabine + Dexamethasone + Mercaptopurine + Pegaspargase + Vincristine Sulfate Bortezomib Cyclophosphamide Cytarabine Dexamethasone Mercaptopurine Pegaspargase Vincristine Sulfate 0 0
Bortezomib + Cyclophosphamide + Daratumumab + Dexamethasone Bortezomib Cyclophosphamide Daratumumab Dexamethasone 0 4
Bortezomib + Cyclophosphamide + Dexamethasone + Isatuximab Bortezomib Cyclophosphamide Dexamethasone Isatuximab 0 2
Bortezomib + Cyclophosphamide + Dexamethasone + Pembrolizumab Bortezomib Cyclophosphamide Dexamethasone Pembrolizumab 0 1
Bortezomib + Cyclophosphamide + Doxorubicin + Ibrutinib + Prednisone + Rituximab + Vincristine Sulfate Bortezomib Cyclophosphamide Doxorubicin Ibrutinib Prednisone Rituximab Vincristine Sulfate 0 1
Bortezomib + Cyclophosphamide + Filgrastim Bortezomib Cyclophosphamide Filgrastim 0 1
Bortezomib + Cyclophosphamide + Lenalidomide Bortezomib Cyclophosphamide Lenalidomide 0 1
Bortezomib + Cyclosporine + Mycophenolate mofetil Bortezomib Cyclosporine Mycophenolate mofetil 0 1
Bortezomib + Cytarabine + Etoposide + Midostaurin + Mitoxantrone Bortezomib Cytarabine Etoposide Midostaurin Mitoxantrone 0 0
Bortezomib + Daratumumab + Dexamethasone Bortezomib Daratumumab Dexamethasone 0 10
Bortezomib + Daratumumab + Dexamethasone + Iberdomide Bortezomib Daratumumab Dexamethasone Iberdomide 0 1
Bortezomib + Daratumumab + Dexamethasone + Lenalidomide Bortezomib Daratumumab Dexamethasone Lenalidomide 0 15
Bortezomib + Daratumumab + Dexamethasone + Lenalidomide + Talquetamab-tgvs + Teclistamab Bortezomib Daratumumab Dexamethasone Lenalidomide Talquetamab-tgvs Teclistamab 0 0
Bortezomib + Daratumumab + Dexamethasone + Lenalidomide + Teclistamab Bortezomib Daratumumab Dexamethasone Lenalidomide Teclistamab 0 1
Bortezomib + Daratumumab + Dexamethasone + Melphalan + Prednisone Bortezomib Daratumumab Dexamethasone Melphalan Prednisone 0 1
Bortezomib + Daratumumab + Dexamethasone + Selinexor Bortezomib Daratumumab Dexamethasone Selinexor 0 2
Bortezomib + Daratumumab + Dexamethasone + Thalidomide Bortezomib Daratumumab Dexamethasone Thalidomide 0 1
Bortezomib + Daratumumab + Dexamethasone + Venetoclax Bortezomib Daratumumab Dexamethasone Venetoclax 0 2
Bortezomib + Daratumumab + Lenalidomide + Teclistamab Bortezomib Daratumumab Lenalidomide Teclistamab 0 1
Bortezomib + Daratumumab + Melphalan Bortezomib Daratumumab Melphalan 0 0
Bortezomib + Daratumumab + Melphalan + Prednisone Bortezomib Daratumumab Melphalan Prednisone 0 0
Bortezomib + Daratumumab and hyaluronidase-fihj + Dexamethasone Bortezomib Daratumumab and hyaluronidase-fihj Dexamethasone 0 0
Bortezomib + Daratumumab and hyaluronidase-fihj + Dexamethasone + Lenalidomide Bortezomib Daratumumab and hyaluronidase-fihj Dexamethasone Lenalidomide 0 1
Bortezomib + Daratumumab and hyaluronidase-fihj + Dexamethasone + Panobinostat Bortezomib Daratumumab and hyaluronidase-fihj Dexamethasone Panobinostat 0 1
Bortezomib + Daratumumab and hyaluronidase-fihj + Dexamethasone + Selinexor Bortezomib Daratumumab and hyaluronidase-fihj Dexamethasone Selinexor 0 1
Bortezomib + Daratumumab and hyaluronidase-fihj + Melphalan + Prednisone Bortezomib Daratumumab and hyaluronidase-fihj Melphalan Prednisone 0 0
Bortezomib + Dasatinib + Dexamethasone + Doxorubicin + Palbociclib Bortezomib Dasatinib Dexamethasone Doxorubicin Palbociclib 0 1
Bortezomib + Decitabine + Sorafenib Bortezomib Decitabine Sorafenib 0 1
Bortezomib + Dexamethasone Bortezomib Dexamethasone 0 8
Bortezomib + Dexamethasone + Dinaciclib Bortezomib Dexamethasone Dinaciclib 0 1
Bortezomib + Dexamethasone + Doxorubicin + Methotrexate + Pegaspargase + Vincristine Sulfate Bortezomib Dexamethasone Doxorubicin Methotrexate Pegaspargase Vincristine Sulfate 0 1
Bortezomib + Dexamethasone + Doxorubicin + Palbociclib Bortezomib Dexamethasone Doxorubicin Palbociclib 0 1
Bortezomib + Dexamethasone + Elotuzumab + Lenalidomide Bortezomib Dexamethasone Elotuzumab Lenalidomide 0 1
Bortezomib + Dexamethasone + Elotuzumab + Panobinostat Bortezomib Dexamethasone Elotuzumab Panobinostat 0 1
Bortezomib + Dexamethasone + Hu5F9-G4 Bortezomib Dexamethasone Hu5F9-G4 0 1
Bortezomib + Dexamethasone + Iberdomide Bortezomib Dexamethasone Iberdomide 0 1
Bortezomib + Dexamethasone + Iberdomide + Isatuximab Bortezomib Dexamethasone Iberdomide Isatuximab 0 1
Bortezomib + Dexamethasone + Iberdomide + Isatuximab + Lenalidomide Bortezomib Dexamethasone Iberdomide Isatuximab Lenalidomide 0 1
Bortezomib + Dexamethasone + Idecabtagene Vicleucel + Pomalidomide Bortezomib Dexamethasone Idecabtagene Vicleucel Pomalidomide 0 1
Bortezomib + Dexamethasone + Isatuximab Bortezomib Dexamethasone Isatuximab 0 1
Bortezomib + Dexamethasone + Isatuximab + Lenalidomide Bortezomib Dexamethasone Isatuximab Lenalidomide 0 7
Bortezomib + Dexamethasone + Lenalidomide Bortezomib Dexamethasone Lenalidomide 0 16
Bortezomib + Dexamethasone + Lenalidomide + Melphalan + Prednisone Bortezomib Dexamethasone Lenalidomide Melphalan Prednisone 0 1
Bortezomib + Dexamethasone + Lenalidomide + Mezagitamab Bortezomib Dexamethasone Lenalidomide Mezagitamab 0 1
Bortezomib + Dexamethasone + Lenalidomide + Panobinostat Bortezomib Dexamethasone Lenalidomide Panobinostat 0 2
Bortezomib + Dexamethasone + LGH447 Bortezomib Dexamethasone LGH447 0 0
Bortezomib + Dexamethasone + Linsitinib Bortezomib Dexamethasone Linsitinib 0 1
Bortezomib + Dexamethasone + Linvoseltamab Bortezomib Dexamethasone Linvoseltamab 0 1
Bortezomib + Dexamethasone + Melflufen Bortezomib Dexamethasone Melflufen 0 1
Bortezomib + Dexamethasone + Melphalan + Thalidomide Bortezomib Dexamethasone Melphalan Thalidomide 0 2
Bortezomib + Dexamethasone + Panobinostat Bortezomib Dexamethasone Panobinostat 0 4
Bortezomib + Dexamethasone + Pelareorep Bortezomib Dexamethasone Pelareorep 0 1
Bortezomib + Dexamethasone + Pelareorep + Pembrolizumab Bortezomib Dexamethasone Pelareorep Pembrolizumab 0 1
Bortezomib + Dexamethasone + Pembrolizumab Bortezomib Dexamethasone Pembrolizumab 0 1
Bortezomib + Dexamethasone + Pomalidomide Bortezomib Dexamethasone Pomalidomide 0 9
Bortezomib + Dexamethasone + Radium Ra 223 dichloride Bortezomib Dexamethasone Radium Ra 223 dichloride 0 1
Bortezomib + Dexamethasone + Ricolinostat Bortezomib Dexamethasone Ricolinostat 0 0
Bortezomib + Dexamethasone + Selinexor Bortezomib Dexamethasone Selinexor 0 3
Bortezomib + Dexamethasone + Thalidomide Bortezomib Dexamethasone Thalidomide 0 1
Bortezomib + Dexamethasone + Ulocuplumab Bortezomib Dexamethasone Ulocuplumab 0 1
Bortezomib + Dexamethasone + Venetoclax Bortezomib Dexamethasone Venetoclax 0 2
Bortezomib + DT204 Bortezomib DT204 0 0
Bortezomib + Duvelisib Bortezomib Duvelisib 0 1
Bortezomib + Everolimus Bortezomib Everolimus 0 1
Bortezomib + Fasudil Bortezomib Fasudil 0 0
Bortezomib + Filgrastim Bortezomib Filgrastim 0 2
Bortezomib + Fludarabine + Melphalan Bortezomib Fludarabine Melphalan 0 1
Bortezomib + Gemtuzumab ozogamicin Bortezomib Gemtuzumab ozogamicin 0 1
Bortezomib + GO-203-2C Bortezomib GO-203-2C 0 1
Bortezomib + Ibrutinib Bortezomib Ibrutinib 0 1
Bortezomib + Lapatinib Bortezomib Lapatinib 0 1
Bortezomib + Lenalidomide Bortezomib Lenalidomide 0 1
Bortezomib + Lenalidomide + PAT-SM6 Bortezomib Lenalidomide PAT-SM6 0 0
Bortezomib + Lenalidomide + Rituximab Bortezomib Lenalidomide Rituximab 0 1
Bortezomib + Melphalan + Prednisone Bortezomib Melphalan Prednisone 0 1
Bortezomib + Metformin + Nelfinavir Bortezomib Metformin Nelfinavir 0 1
Bortezomib + Mivebresib Bortezomib Mivebresib 0 0
Bortezomib + MKC-3946 Bortezomib MKC-3946 0 0
Bortezomib + Molibresib Bortezomib Molibresib 0 0
Bortezomib + Oxaliplatin Bortezomib Oxaliplatin 0 1
Bortezomib + Palbociclib Bortezomib Palbociclib 0 1
Bortezomib + Panobinostat Bortezomib Panobinostat 0 0
Bortezomib + Pegylated liposomal doxorubicin Bortezomib Pegylated liposomal doxorubicin 0 1
Bortezomib + Plerixafor Bortezomib Plerixafor 0 1
Bortezomib + Pomalidomide + TAK-573 Bortezomib Pomalidomide TAK-573 0 1
Bortezomib + Pravastatin Bortezomib Pravastatin 0 1
Bortezomib + Ribociclib Bortezomib Ribociclib 0 0
Bortezomib + Rituximab Bortezomib Rituximab 0 2
Bortezomib + Rituximab + Venetoclax Bortezomib Rituximab Venetoclax 0 1
Bortezomib + Ruxolitinib Bortezomib Ruxolitinib 0 1
Bortezomib + SJB3-019A Bortezomib SJB3-019A 0 0
Bortezomib + Sonidegib Bortezomib Sonidegib 0 1
Bortezomib + Sorafenib + Vorinostat Bortezomib Sorafenib Vorinostat 0 1
Bortezomib + Tabalumab Bortezomib Tabalumab 0 0
Bortezomib + TAK-573 Bortezomib TAK-573 0 1
Bortezomib + Temozolomide Bortezomib Temozolomide 0 2
Bortezomib + Temsirolimus + Topotecan Bortezomib Temsirolimus Topotecan 1 0
Bortezomib + Tinostamustine Bortezomib Tinostamustine 0 0
Bortezomib + Torkinib Bortezomib Torkinib 0 0
Bortezomib + Vorinostat Bortezomib Vorinostat 0 0


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