Darinaparsin
Drug Detail
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| Drug Name | Darinaparsin |
| Trade Name | |
| Synonyms | ZIO-101|ZIO101|ZIO 101|S-Dimethylarsino-Glutathione|DMAIII(SG) |
| Drug Descriptions |
Darinaparsin is an arsenic derivative that activates MAPK signaling and inhibits Hedgehog signaling (PMID: 25381261, 25316819), and potentially leads to tumor cell killing and inhibition of tumor growth (PMID: 25381261, PMID: 25316819, PMID: 30080396). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C61490 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Darinaparsin | Darinaparsin | 0 | 0 |
| Darinaparsin + Docetaxel | Darinaparsin Docetaxel | 0 | 0 |
| Darinaparsin + Selumetinib | Darinaparsin Selumetinib | 0 | 0 |
| Darinaparsin + U0126 | Darinaparsin U0126 | 0 | 0 |
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