U0126
Drug Detail
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| Drug Name | U0126 |
| Trade Name | |
| Synonyms | |
| Drug Descriptions |
U0126 binds and inhibits Mek1 and Mek2, which may inhibit the activation of downstream signaling targets and reduce tumor cell proliferation (PMID: 9873633). |
| DrugClasses | MEK inhibitor (Pan) 27 MEK1 Inhibitor 27 MEK2 Inhibitor 25 |
| CAS Registry Number | 1173097-76-1 |
| NCIT ID | NA |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Cetuximab + U0126 | Cetuximab U0126 | 0 | 0 |
| Dactolisib + U0126 | Dactolisib U0126 | 0 | 0 |
| Darinaparsin + U0126 | Darinaparsin U0126 | 0 | 0 |
| Everolimus + U0126 | Everolimus U0126 | 1 | 0 |
| Torkinib + U0126 | Torkinib U0126 | 1 | 0 |
| U0126 | U0126 | 9 | 0 |
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