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Drug Name | U0126 |
Trade Name | |
Synonyms | |
Drug Descriptions |
U0126 binds and inhibits Mek1 and Mek2, which may inhibit the activation of downstream signaling targets and reduce tumor cell proliferation (PMID: 9873633). |
DrugClasses | MEK inhibitor (Pan) 26 MEK1 Inhibitor 26 MEK2 Inhibitor 24 |
CAS Registry Number | 1173097-76-1 |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Cetuximab + U0126 | Cetuximab U0126 | 0 | 0 |
Dactolisib + U0126 | Dactolisib U0126 | 0 | 0 |
Darinaparsin + U0126 | Darinaparsin U0126 | 0 | 0 |
Everolimus + U0126 | Everolimus U0126 | 1 | 0 |
Torkinib + U0126 | Torkinib U0126 | 1 | 0 |
U0126 | U0126 | 6 | 0 |