Idronoxil
Drug Detail
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| Drug Name | Idronoxil |
| Trade Name | |
| Synonyms | Phenoxodiol|NV-06|3-(4-Hydroxyphenyl)-2H-1-benzopyran-7-ol |
| Drug Descriptions |
Idronoxil is an isoflavone analog that leads to decreased Cdk2 activity (PMID: 15833870) and activation of the mitochondrial caspase pathway, and may lead to cell cycle arrest and apoptosis (PMID: 16388521) and decreased proliferation of tumor cells (PMID: 20564423). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C2642 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Carboplatin + Idronoxil | Carboplatin Idronoxil | 0 | 0 |
| Docetaxel + Idronoxil | Docetaxel Idronoxil | 0 | 0 |
| Gemcitabine + Idronoxil | Gemcitabine Idronoxil | 0 | 0 |
| Idronoxil | Idronoxil | 0 | 0 |
| Idronoxil + Paclitaxel | Idronoxil Paclitaxel | 0 | 0 |
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