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Drug Name | KU-59403 |
Trade Name | |
Synonyms | KU59403|KU 59403 |
Drug Descriptions |
KU-59403 is an ATM inhibitor, which upon inhibition of Atm may lead to increased sensitivity to chemotherapuetic agents such as those inducing double strand breaks, and radiotherapy, subsequently resulting in cytotoxicity and antitumor activity (PMID: 23512991). |
DrugClasses | ATM Inhibitor 13 |
CAS Registry Number | 845932-30-1 |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Camptothecin + KU-59403 | Camptothecin KU-59403 | 0 | 0 |
Doxorubicin + KU-59403 | Doxorubicin KU-59403 | 0 | 0 |
Etoposide + KU-59403 | Etoposide KU-59403 | 0 | 0 |
Irinotecan + KU-59403 | Irinotecan KU-59403 | 0 | 0 |
KU-59403 | KU-59403 | 0 | 0 |