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Drug Name | Irinotecan |
Trade Name | Camptosar |
Synonyms | CPT-11 |
Drug Descriptions |
Camptosar (irinotecan) inhibits Topoisomerase-I activity, resulting in inhibition of DNA replication, and potentially leading to cell death and is indicated as a component of first-line therapy in combination with 5-fluorouracil and leucovorin for patients with metastatic or recurrent colorectal carcinoma (FDA.gov). |
DrugClasses | TOPO1 inhibitor 11 |
CAS Registry Number | 136572-09-3 |
NCIT ID | C1381 |