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| Drug Name | NBE-002 |
| Trade Name | |
| Synonyms | NBE002|NBE 002|iADC NBE-002|Anti-ROR1/PNU-159682 Derivative ADC NBE-002 |
| Drug Descriptions |
NBE-002 is a next-generation antibody drug conjugate consisting of a humanized monoclonal antibody directed against the receptor tyrosine kinase ROR1, site-specifically conjugated to a derivative of the highly potent anthracycline PNU-159682, potentially leading to inhibition of DNA replication and repair and may inhibit tumor cell proliferation and survival (Cancer Research, 79(13), LB-197, doi: 10.1158/1538-7445.AM2019-LB-197). |
| DrugClasses | ROR1 Antibody 7 |
| CAS Registry Number | NA |
| NCIT ID | C174012 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| NBE-002 | NBE-002 | 0 | 1 |
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