IL13 [EQ]BBzeta/truncated CD19[t]+ TN/MEM cells
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| Drug Name | IL13 [EQ]BBzeta/truncated CD19[t]+ TN/MEM cells |
| Trade Name | |
| Synonyms | IL13 [EQ]BBzeta/truncated CD19[t]+ Naive and Memory T Cells |
| Drug Descriptions |
IL13 [EQ]BBzeta/truncated CD19[t]+ TN/MEM cells are autologous naïve and memory T cells (TN/MEM) engineered to express a chimeric antigen receptor (CAR) targeting interleukin-13 receptor alpha 2 (IL13Ra2), and containing the CD137 co-stimulatory signaling domain fused to CD3-zeta, and a truncated form of CD19, which may induce killing of to IL13Ra2-expressing tumor cells (NCI Drug Dictionary). |
| DrugClasses | IL13RA2 Immune Cell Therapy 7 |
| CAS Registry Number | NA |
| NCIT ID | C141460 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| IL13 [EQ]BBzeta/truncated CD19[t]+ TN/MEM cells | IL13 [EQ]BBzeta/truncated CD19[t]+ TN/MEM cells | 0 | 0 |
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