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Therapy Name IL13 [EQ]BBzeta/truncated CD19[t]+ TN/MEM cells
Synonyms
Therapy Description

IL13 [EQ]BBzeta/truncated CD19[t]+ TN/MEM cells are autologous naïve and memory T cells (TN/MEM) engineered to express a chimeric antigen receptor (CAR) targeting interleukin-13 receptor alpha 2 (IL13Ra2), and containing the CD137 co-stimulatory signaling domain fused to CD3-zeta, and a truncated form of CD19, which may induce killing of to IL13Ra2-expressing tumor cells (NCI Drug Dictionary).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
IL13 [EQ]BBzeta/truncated CD19[t]+ TN/MEM cells IL13 [EQ]BBzeta/truncated CD19[t]+ Naive and Memory T Cells IL13RA2 Immune Cell Therapy 7 IL13 [EQ]BBzeta/truncated CD19[t]+ TN/MEM cells are autologous naïve and memory T cells (TN/MEM) engineered to express a chimeric antigen receptor (CAR) targeting interleukin-13 receptor alpha 2 (IL13Ra2), and containing the CD137 co-stimulatory signaling domain fused to CD3-zeta, and a truncated form of CD19, which may induce killing of to IL13Ra2-expressing tumor cells (NCI Drug Dictionary).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries


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