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Drug Name | Metarrestin |
Trade Name | |
Synonyms | ML-246|ML 246|ML246 |
Drug Descriptions |
Metarrestin is a small molecule drug that inhibits the assembly of the perinucleolar compartment, leading to disruption of the nucleolar structure and inhibition of RNA polymerase I transcription, which may result in decreased metastasis, including reduced cell growth and invasion and decreased tumor growth (PMID: 29769289). |
DrugClasses | |
CAS Registry Number | 1443414-10-5 |
NCIT ID | C168544 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Metarrestin | Metarrestin | 0 | 1 |