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Drug Name | Simmiparib |
Trade Name | |
Synonyms | SMOCL-9112 |
Drug Descriptions |
Simmiparib is an inhibitor of PARP1/2, which may induce DNA double-strand breaks, G2/M phase arrest, and apoptotic activity, and may lead to inhibition of tumor growth (PMID: 27847302). |
DrugClasses | PARP Inhibitor (Pan) 31 |
CAS Registry Number | 1551355-46-4 |
NCIT ID | C140553 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
CHIR99021 + Simmiparib | CHIR99021 Simmiparib | 0 | 0 |
LY2090314 + Simmiparib | LY2090314 Simmiparib | 0 | 0 |
Simmiparib | Simmiparib | 0 | 0 |