Simmiparib
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| Drug Name | Simmiparib |
| Trade Name | |
| Synonyms | SMOCL-9112 |
| Drug Descriptions |
Simmiparib is an inhibitor of PARP1/2, which may induce DNA double-strand breaks, G2/M phase arrest, and apoptotic activity, and may lead to inhibition of tumor growth (PMID: 27847302). |
| DrugClasses | PARP Inhibitor (Pan) 29 |
| CAS Registry Number | 1551355-46-4 |
| NCIT ID | C140553 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| CHIR99021 + Simmiparib | CHIR99021 Simmiparib | 0 | 0 |
| LY2090314 + Simmiparib | LY2090314 Simmiparib | 0 | 0 |
| Simmiparib | Simmiparib | 0 | 0 |
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