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| Drug Name | LY2090314 |
| Trade Name | |
| Synonyms | LY-2090314|LY 2090314 |
| Drug Descriptions |
LY2090314 inhibits glycogen synthase kinase 3 (GSK3), therefore activates Wnt signaling pathway and leads to apoptosis in tumor cells (PMID: 25915038, PMID: 26735141, PMID: 32391602). |
| DrugClasses | GSK3 Inhibitor (Pan) 3 |
| CAS Registry Number | 603288-22-8 |
| NCIT ID | C116849 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Carboplatin + LY2090314 + Pemetrexed Disodium | Carboplatin LY2090314 Pemetrexed Disodium | 0 | 0 |
| LY2090314 | LY2090314 | 0 | 0 |
| LY2090314 + Niraparib | LY2090314 Niraparib | 0 | 0 |
| LY2090314 + Olaparib | LY2090314 Olaparib | 0 | 0 |
| LY2090314 + Rucaparib | LY2090314 Rucaparib | 0 | 0 |
| LY2090314 + Simmiparib | LY2090314 Simmiparib | 0 | 0 |
| LY2090314 + Talazoparib | LY2090314 Talazoparib | 0 | 0 |
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