ENB003
Drug Detail
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| Drug Name | ENB003 |
| Trade Name | |
| Synonyms | ENB-003|ENB 003|Vodudeutentan Sodium |
| Drug Descriptions |
ENB003 is an an antagonist that selectively binds to endothelin B receptor (ETBR) and inhibits downstream signaling, which potentially relieves tumor immunosuppression and inhibits proliferation of tumor cells expressing ETBR (Clin Cancer Res 2009;15(14):4521-4528; NCI Drug Dictionary). |
| DrugClasses | |
| CAS Registry Number | 2364572-10-9 |
| NCIT ID | C175447 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| ENB003 | ENB003 | 0 | 0 |
| ENB003 + Pembrolizumab | ENB003 Pembrolizumab | 0 | 1 |
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