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Drug Name | TAS-117 |
Trade Name | |
Synonyms | TAS117|TAS 117 |
Drug Descriptions |
TAS-117 is a selective allosteric inhibitor of Akt that inhibits Akt phosphorylation and downstream signaling, potentially leading to cytoxicity in tumor cells and decreased tumor growth (PMID: 24934808). |
DrugClasses | Akt Inhibitor (Pan) 21 |
CAS Registry Number | 1402602-94-1 |
NCIT ID | C178300 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Futibatinib + TAS-117 | Futibatinib TAS-117 | 0 | 0 |
TAS-117 | TAS-117 | 4 | 1 |