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Drug Name | Futibatinib |
Trade Name | Lytgobi |
Synonyms | TAS-120 |
Drug Descriptions |
Lytgobi (futibatinib) is a third-generation pan-FGFR inhibitor, which results in the inhibition of FGFR-mediated signal transduction pathways and tumor cell proliferation (PMID: 31109923). Lytgobi (futibatinib) is FDA approved for use in patients with previously treated, unresectable, locally advanced or metastatic intrahepatic cholangiocarcinoma harboring FGFR2 fusion or rearrangement (FDA.gov). |
DrugClasses | FGFR Inhibitor (Pan) 26 |
CAS Registry Number | 1448169-71-8 |
NCIT ID | C114283 |