ABBV-CLS-484
Drug Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Drug Name | ABBV-CLS-484 |
| Trade Name | |
| Synonyms | ABBV CLS 484|ABBV CLS484|AC484 |
| Drug Descriptions |
ABBV-CLS-484 is a PTPN2/PTPN1 inhibitor, which activates JAK/STAT signaling, leading to remodeling of the tumor microenvironment, and potentially activation of an antitumor immune response and tumor growth inhibition (PMID: 37794185). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C179723 |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
- Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
- Click on any column header arrows to sort by that column
- Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| ABBV-CLS-484 | ABBV-CLS-484 | 0 | 1 |
| ABBV-CLS-484 + unspecified PD-1 antibody | ABBV-CLS-484 unspecified PD-1 antibody | 0 | 1 |
| ABBV-CLS-484 + unspecified VEGFR inhibitor | ABBV-CLS-484 unspecified VEGFR inhibitor | 0 | 1 |
CKB BOOST