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Drug Name ABBV-CLS-484
Trade Name
Synonyms ABBV CLS 484|ABBV CLS484|AC484
Drug Descriptions

ABBV-CLS-484 is a PTPN2/PTPN1 inhibitor, which activates JAK/STAT signaling, leading to remodeling of the tumor microenvironment, and potentially activation of an antitumor immune response and tumor growth inhibition (PMID: 37794185).

DrugClasses
CAS Registry Number NA
NCIT ID C179723

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Therapy Name Drugs Efficacy Evidence Clinical Trials
ABBV-CLS-484 ABBV-CLS-484 0 1
ABBV-CLS-484 + unspecified PD-1 antibody ABBV-CLS-484 unspecified PD-1 antibody 0 1


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