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Drug Name | ABBV-CLS-484 |
Trade Name | |
Synonyms | ABBV CLS 484|ABBV CLS484|AC484 |
Drug Descriptions |
ABBV-CLS-484 is a PTPN2/PTPN1 inhibitor, which activates JAK/STAT signaling, leading to remodeling of the tumor microenvironment, and potentially activation of an antitumor immune response and tumor growth inhibition (PMID: 37794185). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C179723 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
ABBV-CLS-484 | ABBV-CLS-484 | 0 | 1 |
ABBV-CLS-484 + unspecified PD-1 antibody | ABBV-CLS-484 unspecified PD-1 antibody | 0 | 1 |