E7777
Drug Detail
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| Drug Name | E7777 |
| Trade Name | |
| Synonyms | E-7777|E 7777 |
| Drug Descriptions |
E7777 is a recombinant protein consisting of the binding domain of the cytokine IL-2 fused to fragments A and B of the diphtheria toxin, which binds to the IL-2 receptor on tumor cells, and following endocytosis leads to inhibition of protein synthesis, potentially resulting in cell death (PMID: 33792128, NCI Thesaurus). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C126273 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| E7777 | E7777 | 0 | 2 |
| E7777 + Pembrolizumab | E7777 Pembrolizumab | 0 | 1 |
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