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Drug Name | HDP-101 |
Trade Name | |
Synonyms | HDP101 |
Drug Descriptions |
HDP-101 is an antibody-drug conjugate (ADC) comprising an antibody targeting the anti-B cell maturation antigen (BCMA) linked to a derivative of amanitin, which binds to BCMA-positive tumor cells, potentially leading to induction of apoptosis, tumor cell killing, and inhibition of tumor growth (PMID: 33298585). |
DrugClasses | TNFRSF17 Antibody 20 |
CAS Registry Number | NA |
NCIT ID | C179409 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Carfilzomib + HDP-101 | Carfilzomib HDP-101 | 0 | 0 |
Dexamethasone + HDP-101 | Dexamethasone HDP-101 | 0 | 0 |
HDP-101 | HDP-101 | 0 | 1 |