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| Drug Name | BI 765049 |
| Trade Name | |
| Synonyms | BI-765049|BI765049 |
| Drug Descriptions |
BI 765049 is a bispecific T-cell engager (BiTE) that targets tumor-expressed NCR3LG1 (B7-H6) and CD3 expressed on T-cells, potentially leading to increased migration of T-lymphocytes to the tumor, resulting in tumor cell apoptosis and decreased tumor growth (J Clin Oncol 40, no. 16_suppl (June 01, 2022) TPS3175-TPS3175). |
| DrugClasses | CD3 Antibody 119 |
| CAS Registry Number | NA |
| NCIT ID | NA |
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| BI 765049 | BI 765049 | 0 | 2 |
| BI 765049 + Ezabenlimab | BI 765049 Ezabenlimab | 0 | 1 |