PY314
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| Drug Name | PY314 |
| Trade Name | |
| Synonyms | PY-314|PY 314 |
| Drug Descriptions |
PY314 is a monoclonal antibody that targets TREM2 expressed on tumor-associated macrophages (TAMs), potentially resulting in depletion of M2-like TAMs, activation of the immune response, and anti-tumor activity (Mol Cancer Ther 2019;18(12 Suppl):Abstract nr C104). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C179597 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Pembrolizumab + PY314 | PY314 Pembrolizumab | 0 | 1 |
| PY314 | PY314 | 0 | 1 |
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