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Drug Name | CC-96673 |
Trade Name | |
Synonyms | CC 96673|CC96673|BMS-986358|BMS 986358|BMS986358 |
Drug Descriptions |
CC-96673 is a bispecific antibody that targets CD20 with high affinity and CD47 with low affinity and inhibits the interaction of CD47 with SIRPa, which potentially induces antibody-dependent cellular cytotoxicity and complement-dependent cytotoxicity against CD20-expressing tumor cells, increases phagocytosis of tumor cells, and inhibits tumor growth (PMID: 38349008). |
DrugClasses | CD20 Antibody 25 CD47 Antibody 31 |
CAS Registry Number | NA |
NCIT ID | C204503 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
CC-96673 | CC-96673 | 0 | 1 |