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Therapy Name | CC-96673 |
Synonyms | |
Therapy Description |
CC-96673 is a bispecific antibody that targets CD20 with high affinity and CD47 with low affinity and inhibits the interaction of CD47 with SIRPa, which potentially induces antibody-dependent cellular cytotoxicity and complement-dependent cytotoxicity against CD20-expressing tumor cells, increases phagocytosis of tumor cells, and inhibits tumor growth (PMID: 38349008). |