Zidesamtinib
Drug Detail
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| Drug Name | Zidesamtinib |
| Trade Name | Jideytro |
| Synonyms | NVL-520|NUV 520|NUV520|NVL 520|NVL520|SIM18031A|NUV-520 |
| Drug Descriptions |
Jideytro (zidesamtinib) is a brain-penetrant small-molecule inhibitor of ROS1, which potentially inhibits ROS1 kinase activity, decreases tumor cell viability, and reduces tumor growth (PMID: 40299789). Jideytro (zidesamtinib) is FDA-approved for use in patients with locally advanced or metastatic ROS1-positive non-small cell lung cancer who have received prior ROS1 tyrosine kinase inhibitor (FDA.gov). |
| DrugClasses | ROS1 Inhibitor 23 |
| CAS Registry Number | 2739829-00-4 |
| NCIT ID | C185422 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Zidesamtinib | Zidesamtinib | 4 | 2 |
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