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Drug Name | Exarafenib |
Trade Name | |
Synonyms | KIN-2787|KIN2787|KIN 2787 |
Drug Descriptions |
Exarafenib (KIN-2787) is a small molecule pan-RAF inhibitor with activity against BRAF Class II and Class III mutants, which inhibits downstream signaling, potentially resulting in decreased growth of BRAF-mutant tumors (J Clin Oncol 39, no. 15_suppl (May 20, 2021) 3116-3116). |
DrugClasses | RAF Inhibitor (Pan) 28 |
CAS Registry Number | 2639957-39-2 |
NCIT ID | C180835 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Binimetinib + Exarafenib | Binimetinib Exarafenib | 3 | 1 |
Exarafenib | Exarafenib | 7 | 1 |