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| Drug Name | Binimetinib |
| Trade Name | Mektovi |
| Synonyms | ARRY-162|ARRY-438162|MEK162 |
| Drug Descriptions |
Mektovi (binimetinib) inhibits MEK1 and MEK2 resulting in inhibition of growth factor-mediated signaling and decreased tumor cell proliferation (PMID: 23587417). Mektovi (binimetinib) in combination with Braftovi (encorafenib) is FDA approved for use in patients with unresectable or metastatic melanoma with a BRAF V600E or V600K mutation (FDA.gov). |
| DrugClasses | MEK inhibitor (Pan) 26 MEK1 Inhibitor 26 MEK2 Inhibitor 24 |
| CAS Registry Number | 606143-89-9 |
| NCIT ID | C84865 |
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