Exarafenib
Drug Detail
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| Drug Name | Exarafenib |
| Trade Name | |
| Synonyms | KIN-2787|KIN2787|KIN 2787 |
| Drug Descriptions |
Exarafenib (KIN-2787) is a small molecule pan-RAF inhibitor with activity against BRAF Class II and Class III mutants, which inhibits downstream signaling, potentially resulting in decreased growth of BRAF-mutant tumors (J Clin Oncol 39, no. 15_suppl (May 20, 2021) 3116-3116). |
| DrugClasses | RAF Inhibitor (Pan) 29 |
| CAS Registry Number | 2639957-39-2 |
| NCIT ID | C180835 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Binimetinib + Exarafenib | Binimetinib Exarafenib | 3 | 1 |
| Exarafenib | Exarafenib | 7 | 1 |
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