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Drug Name | THIO |
Trade Name | |
Synonyms | 6-thio-2'-deoxyguanosine|6-thio-dG |
Drug Descriptions |
THIO (6-thio-2'-deoxyguanosine) is precursor nucleoside analogue that incorporates into newly synthesized telomeres, leading to telomere dysfunction and apoptosis in telomerase-positive cells, and potential anti-tumor activity (PMID: 34593527; PMID: 25516420). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Cemiplimab + THIO | Cemiplimab THIO | 0 | 1 |
Radiotherapy + Temozolomide + THIO | Radiotherapy THIO Temozolomide | 0 | 0 |
Radiotherapy + THIO | Radiotherapy THIO | 0 | 0 |
THIO | THIO | 0 | 0 |