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Drug Name 177Lu-girentuximab
Trade Name
Synonyms 177Lu-DOTA-cG250|Lutetium Lu-177 Girentuximab
Drug Descriptions

177Lu-girentuximab is a radioconjugate comprising the radionuclide Lutetium-177 linked to girentuximab, a monoclonal antibody that targets G250, which delivers radiation to tumor cells and potentially results in inhibition of tumor growth (PMID: 14960657, PMID: 22980441).

DrugClasses
CAS Registry Number NA
NCIT ID C66978

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Therapy Name Drugs Efficacy Evidence Clinical Trials
177Lu-girentuximab 177Lu-girentuximab 0 0
177Lu-girentuximab + Cabozantinib + Nivolumab 177Lu-girentuximab Cabozantinib Nivolumab 0 1
177Lu-girentuximab + Nivolumab 177Lu-girentuximab Nivolumab 0 1
177Lu-girentuximab + Peposertib 177Lu-girentuximab Peposertib 0 1


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