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Drug Name | BIO-106 |
Trade Name | |
Synonyms | BIO 106|BIO106 |
Drug Descriptions |
BIO-106 is an antibody-drug conjugate (ADC) comprised of a monoclonal antibody that targets trophoblast cell surface protein 2 (TROP2) linked to an undisclosed tubulin inhibitor, potentially resulting in cell cycle arrest, apoptosis, and decreased proliferation of tumor cells expressing TROP2 (NCI Drug Dictionary). |
DrugClasses | TROP2 Antibody 14 |
CAS Registry Number | NA |
NCIT ID | C187313 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
BIO-106 | BIO-106 | 0 | 1 |
BIO-106 + Pembrolizumab | BIO-106 Pembrolizumab | 0 | 1 |