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Drug Name | Setanaxib |
Trade Name | |
Synonyms | GKT137831 |
Drug Descriptions |
Setanaxib (GKT137831) inhibits NADPH oxidase isoform 1 (NOX1) and isoform 4 (NOX4) (PMID: 20942471), and may potentially alter reactive oxygen species levels and decrease tumor cell growth (PMID: 35326163). |
DrugClasses | |
CAS Registry Number | 1218942-37-0 |
NCIT ID | C166721 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Pembrolizumab + Setanaxib | Pembrolizumab Setanaxib | 0 | 1 |
Setanaxib | Setanaxib | 0 | 0 |