AZD8205
Drug Detail
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| Drug Name | AZD8205 |
| Trade Name | |
| Synonyms | AZD 8205|AZD-8205|Puxitatug Samrotecan |
| Drug Descriptions |
AZD8205 is a an antibody-drug conjugate (ADC) comprising a B7-H4 targeted antibody linked to a topoisomerase inhibitor, which potentially leads to apoptosis of B7-H4-expressing tumor cells and inhibition of tumor growth (Cancer Res 2022;82(12_Suppl):Abstract nr 1765). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C185401 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| AZD2936 + AZD8205 | AZD2936 AZD8205 | 0 | 1 |
| AZD2936 + AZD8205 + AZD9574 | AZD2936 AZD8205 AZD9574 | 0 | 1 |
| AZD2936 + AZD8205 + Saruparib | AZD2936 AZD8205 Saruparib | 0 | 1 |
| AZD8205 | AZD8205 | 0 | 3 |
| AZD8205 + AZD9574 | AZD8205 AZD9574 | 0 | 1 |
| AZD8205 + Saruparib | AZD8205 Saruparib | 0 | 1 |
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