Therapy Detail
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| Therapy Name | AZD8205 |
| Synonyms | |
| Therapy Description |
AZD8205 is a an antibody-drug conjugate (ADC) comprising a B7-H4 targeted antibody linked to a topoisomerase inhibitor, which potentially leads to apoptosis of B7-H4-expressing tumor cells and inhibition of tumor growth (Cancer Res 2022;82(12_Suppl):Abstract nr 1765). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| AZD8205 | AZD 8205|AZD-8205 | AZD8205 is a an antibody-drug conjugate (ADC) comprising a B7-H4 targeted antibody linked to a topoisomerase inhibitor, which potentially leads to apoptosis of B7-H4-expressing tumor cells and inhibition of tumor growth (Cancer Res 2022;82(12_Suppl):Abstract nr 1765). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT05123482 | Phase Ib/II | AZD8205 | First in Human Study to Evaluate AZD8205 in Patients With Advanced or Metastatic Solid Malignancies | Recruiting | USA | POL | NLD | ITA | HUN | GBR | ESP | CAN | BEL | AUS | 5 |
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