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Drug Name | RO7428731 |
Trade Name | |
Synonyms | RO-7428731|RO 7428731 |
Drug Descriptions |
RO7428731 is a bispecific antibody that targets EGFR variant III (EGFRvIII) and CD3, resulting in cross-linking of tumor cells and cytotoxic T-lymphocytes, and potentially leading to increased killing of EGFRvIII-expressing tumor cells (NCI Drug Dictionary). |
DrugClasses | CD3 Antibody 99 |
CAS Registry Number | NA |
NCIT ID | C186377 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
RO7428731 | RO7428731 | 0 | 1 |