Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Drug Name | GB1211 |
| Trade Name | |
| Synonyms | GB-1211|GB 1211|Selvigaltin |
| Drug Descriptions |
GB1211 inhibits galectin-3 and facilitates the binding of anti-PD-1/PD-L1 antibodies to PD-1/PD-L1 respectively, potentially leading to decreased anti-PD-1/PD-L1 resistance (J Clin Oncol 40, no. 16_suppl (June 01, 2022) 2607-2607). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C190361 |
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Atezolizumab + GB1211 | Atezolizumab GB1211 | 0 | 1 |
| Carfilzomib + Daratumumab and hyaluronidase-fihj + Dexamethasone + GB1211 | Carfilzomib Daratumumab and hyaluronidase-fihj Dexamethasone GB1211 | 0 | 1 |
| GB1211 | GB1211 | 0 | 0 |
| GB1211 + Pembrolizumab | GB1211 Pembrolizumab | 0 | 1 |