Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Drug Name | Mubritinib |
Trade Name | |
Synonyms | TAK165|TAK 165|TAK-165 |
Drug Descriptions |
Mubritinib (TAK-165) selectively inhibits ERBB2 (HER2), potentially resulting in oxidative stress, apoptosis (PMID: 31287994), decreased tumor cell viability (PMID: 34715459), and reduced tumor cell proliferation and tumor growth (PMID: 16771730). |
DrugClasses | HER2 Inhibitor 42 |
CAS Registry Number | 366017-09-6 |
NCIT ID | C66212 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Mubritinib | Mubritinib | 0 | 0 |
Mubritinib + Sotorasib | Mubritinib Sotorasib | 0 | 0 |