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Drug Name | RP3 |
Trade Name | |
Synonyms | RP 3|RP-3 |
Drug Descriptions |
RP3 is an oncolytic virus engineered to express a cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) targeting antibody, CD40 ligand, and tumor necrosis factor ligand superfamily member 9 (TNFSF9), which may result in activation of anti-tumor immune response and tumor cell killing (NCI Drug Dictionary). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C179624 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Atezolizumab + Bevacizumab + RP3 | Atezolizumab Bevacizumab RP3 | 0 | 2 |
Carboplatin + Paclitaxel + RP3 | Carboplatin Paclitaxel RP3 | 0 | 1 |
Cisplatin + RP3 | Cisplatin RP3 | 0 | 1 |
Nivolumab + RP3 | Nivolumab RP3 | 0 | 1 |
RP3 | RP3 | 0 | 1 |