DB-1303
Drug Detail
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| Drug Name | DB-1303 |
| Trade Name | |
| Synonyms | DB1303|DB 1303|BNT-323|BNT 323|BNT323|Trastuzumab pamirtecan |
| Drug Descriptions |
DB-1303 is an antibody-drug conjugate (ADC) composed of a biosimilar to the ERBB2 (HER2)-targeted antibody Herceptin (trastuzumab) conjugated to the topoisomerase I inhibitor P1003, which potentially leads to growth inhibition of ERBB2 (HER2)-expressing tumor cells and tumor regression (European Journal of Cancer 174 (2022): S91). |
| DrugClasses | HER2 (ERBB2) Antibody 79 HER2 (ERBB2) Antibody-Drug Conjugate 35 |
| CAS Registry Number | 2792722-57-5 |
| NCIT ID | C188319 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| BNT327 + DB-1303 | BNT327 DB-1303 | 0 | 1 |
| DB-1303 | DB-1303 | 0 | 4 |
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