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Drug Name | DB-1303 |
Trade Name | |
Synonyms | DB1303|DB 1303 |
Drug Descriptions |
DB-1303 is an antibody-drug conjugate (ADC) composed of a biosimilar to the ERBB2 (HER2)-targeted antibody Herceptin (trastuzumab) conjugated to the topoisomerase I inhibitor P1003, which potentially leads to growth inhibition of ERBB2 (HER2)-expressing tumor cells and tumor regression (European Journal of Cancer 174 (2022): S91). |
DrugClasses | HER2 (ERBB2) Antibody 76 HER2 (ERBB2) Antibody-Drug Conjugate 33 |
CAS Registry Number | NA |
NCIT ID | C188319 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
DB-1303 | DB-1303 | 0 | 2 |