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Drug Name | CB307 |
Trade Name | |
Synonyms | CB-307|CB 307 |
Drug Descriptions |
CB307 is a bispecific Humabody that acts as an agonist of TNFRSF9 (CD137) and targets prostate-specific membrane antigen (PSMA) and human serum albumin (HSA), potentially inducing T-cell activation against PSMA-expressing tumor cells and inhibiting tumor growth (PMID: 38593226). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C180592 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Atezolizumab + CB307 | Atezolizumab CB307 | 0 | 0 |
CB307 | CB307 | 0 | 1 |
CB307 + Pembrolizumab | CB307 Pembrolizumab | 0 | 0 |