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Drug Name | UCB6114 |
Trade Name | |
Synonyms | UCB 6114|UCB-6114|Ginisortamab |
Drug Descriptions |
UCB6114 is a monoclonal antibody that binds to Gremlin-1, resulting in activation of BMP and potentially leading to anti-tumor activity (Journal of Clinical Oncology 2022 40:4_suppl, TPS221). |
DrugClasses | |
CAS Registry Number | 2390147-17-6 |
NCIT ID | C173701 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Fluorouracil + Leucovorin + Oxaliplatin + UCB6114 | Fluorouracil Leucovorin Oxaliplatin UCB6114 | 0 | 1 |
Trifluridine-tipiracil hydrochloride + UCB6114 | Trifluridine-tipiracil hydrochloride UCB6114 | 0 | 1 |
UCB6114 | UCB6114 | 0 | 1 |