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Drug Name | IBI343 |
Trade Name | |
Synonyms | IBI-343|IBI 343 |
Drug Descriptions |
IBI343 is an antibody-drug conjugate (ADC) comprising an anti-Claudin18.2 (CLDN18.2) monoclonal antibody linked to the topoisomerase I inhibitor exatecan, which potentially induces apoptosis in tumor cells expressing CLDN18.2 and results in antitumor activity (J Clin Oncol 42, 2024 (suppl 16; abstr 3037), NCI Drug Dictionary). |
DrugClasses | CLDN18.2 Antibody 19 |
CAS Registry Number | NA |
NCIT ID | C189808 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
IBI343 | IBI343 | 0 | 1 |